Oleocanthal an extra-virgin olive oil bioactive component

Oleocanthal, a phenolic compound in virgin olive oil, is a potential nutraceutical therapeutic for many health conditions. The Greek physician Hippocrates (460 -370 BC) mentions approximately 60 of them. Oleocanthal inhibits cyclooxygenase 1 and 2 (COX 1 & 2) enzymes in a dose-dependent manner, and mimics the anti-inflammatory action of the synthetic NSAID ibuprofen. Oleocanthal modulates Alzheimer’s disease, by altering the fibrillization of tau protein and by enhancement of β-amyloid clearance from the brain.

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