Randomized, Placebo-controlled Study of a Nutraceutical Based on Hyaluronic Acid, L-carnosine, and Methylsulfonylmethane in Facial Skin Aesthetics and Well-being
Skin aging is related to several interacting factors, including the progressive reduction and alteration of hyaluronic acid and other glycosaminoglicanes; oxidative stress, hyperproduction of free radicals, and impairment of radical scavenging mechanisms, which characterize all aging processes; glycation of different basic elements, namely proteins such as elastin and collagen, with advanced glycation end-product (AGE) formation; photoaging ultraviolet (UV) light exposure; endocrinosenescence, which tends to alter skin metabolism especially in the postmenopausal period in women; and postural/gravity interaction with skin sagging.1,2
